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Objective:To explore the cystitis glandularis(CG)imaging performance and differential diagnosis between heavily T2WI(T2 weighted)VE(Virtual Endoscop)and Gd-DTPA enhancement TIWI(T1 weighted)VE Methods:1..28 CG cases were confirmed by pathology,all patients scaned by heavily T2WI 3Dsequence and Gd-DTPA enhancement TIWI 3D sequence,All of the imaging and clinical data were retrospectively analyzed.2.Using Siemens trio 3.0 T MRI.Two sequences are using coronary azimuth sca-40 mm,and fat-suppressed ; Gd-DTPA enhancement TIWI selection sequence for 3D truefisp with fat suppression,tissue thickness 30-40 mm; 1.25-1.5 mm thick,no interval,double contrast agent dosage is general; 30 min-2 h with delayed scan,the required delay time will be subject to satisfactory image.3.Imaging data reconstruction was managed by MIP(maximum intensity p Results:In 28 CG cases,flower lawn type thickening are 15 cases,accounting for 53%; Diffuse type are 7 cases,accounting for 25%;Nodular uplift type are 3 ca Combined with clinical data analysis can be obtained : Both heavily T2WI VE and Gd-DTPA enhancement TIWI VE can be clearly showed the bottom or neck of the bladder gland inflammation pathological changes and shape,size,location(P ≤ 0.01).Gd-DTPA enhancement TIWI VE can also prompt scan lesions in mild enhancement.conclusion1.Both heavily T2WI VE and Gd-DTPA enhancement TIWI VE can display of the imaging characteristic of the bladder lumen.Such as;Lesions form,size,location,etc.2.Because of MRI scan time is long,Imaging is easy to constrained by some physical factors.Such as Patients bladder degree of filling,hold breath,the intestina bladder movement,etc.So,before the check,we should make sure the patients prepared higher urine in bladder,To pressurized pelvic in order to reduce the physiological motion artifact,etc.3.Gd-DTPA enhancement TIWI VE can provide bladder cavity lesions information,Due to enhanced features,The original image data can show reach of the diseased organs and blood flow,In the lesions image,Gd-DTPA enhancement TIWI were slightly high signal,and bladder cancer is high signal.So,CG carries some characteristic signs on Gd-DTPA enhancement TIWI VE sequence,which are useful for its diagnosis and for differentiating it from the carcinoma of the urinary bladder.