源于动物血清白蛋白的一个短肽对造血细胞的增殖作用

来源 :华东六省一市生物化学与分子生物学会2008年学术交流会 | 被引量 : 0次 | 上传用户:erwewrasfrfa
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  Chemotherapy-induced myelosuppression and aplastic anemia are bone marrow failure syndromes characterized by peripheral pancytopenia and marrow hypoplasia.Few good therapeutics have been developed to solve the problems.We have identified a novel peptide(PP),derived from serum albumin,with a potent activity to stimulate hematopoietic cells proliferation.Assay of proliferation in vitro was carried out with human haematopoietic stem cells (CD34+)and bone marrow nucleated cells from healthy volunteers and aplastic anemia patientsbone marrow (donors), respectively.
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