【摘 要】
：
Objectives: To investigate the distribution of IgG subclasses in lupus nephritis (LN) and analyze its correlation with the imbalance of Th 1/Th2.Methods: Renal biopsys of 124 SLE patients (type Ⅱ , 17
【机 构】
：
广东医学院附属医院肾病内科(肾脏疾病研究所)
【出 处】
：
中国免疫学会第九届全国免疫学学术大会
论文部分内容阅读
Objectives: To investigate the distribution of IgG subclasses in lupus nephritis (LN) and analyze its correlation with the imbalance of Th 1/Th2.Methods: Renal biopsys of 124 SLE patients (type Ⅱ , 17;type Ⅳ, 80;type Ⅴ , 6;type Ⅴ + Ⅳ, 21).Immunofluorescence with FITC-anti-huamn-IgG1, IgG2, IgG3 and IgG4 were used to detect the deposition of IgG subclasses in renal tissues, respectively.Then we analyzed their relevance.
其他文献
Our earlier study has reported that active vitamin D deficiency in mice causes secondary hypertension and cardiac dysfunction, but underlying mechanism is still largely unknown.To clarify whether exog
Dissociated adult DRG neurons offer the possibility to study mature neurons that may better resemble the in vivo characteristics of these cells.However, adult DRG neurons culture is a complex, time-co
Objective: To clarify the morbidity and clinical features of myasthenia gravis (MG) in Henan Province, China.Patients and Methods: Total 478 MG patients were included, from January, 2010 to February,
IL-25 is an important immune regulator which can promote Th2 immune response-dependent immunity, inflammation, and tissue repair in asthma, intestinal infection and autoimmune diseases.In the present
INTRODUCTION: Methyl salicylate 2-O-β-D-lactoside (MSL), whose chemical structure is similar to that of salicylic acid, is a natural product derivative isolated from a traditional Chinese herb.The aim
TGF-β and IL-2 are two important cytokines in regulating the balance between regulatory T cells and conventional T cells, thus the homeostasis of the immune system.To investigate the synergetic role o
目的:肺结核合并糖尿病(TB+DM)在临床上较为常见,并且与肺结核患者(TB)相比TB+DM更难于治愈.最近研究发现,T细胞在活化、记忆T细胞的形成过程中经历不同的代谢改变,活化的效应T细胞具有较强的糖酵解代谢.目前对TB+DM患者中结核抗原特异性的T细胞功能的报道较少,尤其是糖尿病(DM)导致的代谢紊乱对结核特异性T细胞反应的影响还知之甚少.本研究将比较分析TB+DM与TB患者中结核特异性多功能
Objective: A large scale replication study based on genome wide association study (GWAS) has implicated IκB kinase β (IKBKB) gene as genetic risk factors associated with Systemic lupus erythematosus (
Objective: Previous studies suggested a pathological role for the death decoy receptor 3 (DcR3) in systemic lupus erythematosus (SLE) and rheumatic arthritis (RA).Herein, the expression of DcR3 in pri
Background: Type 1 diabetes mellitus (T1DM) is associated with an increased cardiovascular (CV) morbidity and mortality as compared with the general population.Cardiovascular disease is based on ather