The anti-arrhythmic properties of renin-angiotensin system blockers (RASB (ACE_I; ARB)) have been demonstrated in several studies.However, the role of RASB for maintenance of sinus rhythm in patients with AF after pulmonary vein isolation (PVI) is poorly investigated.The goal of this analysis was to identify cohort of patients with AF and hypertension, who may have benefit from upstream therapy including PVI and following RASB administration.A total of 274 consecutive patients with symptomatic AF and hypertension (paroxysmal AF (PAF) =210, male=177, age=61 years, LVEF=60%, CAD=38) were included in the study: 189 patients were treated with RF-based ablation and in 85 patients PVs were isolated using cryo balloon.A 7-day continuous Holter ECG was performed after discharge and every three months.