What is the Best Column Thermostatting Technique in the Presence of Viscous Heating?

来源 :43rd International Symposium on High Performance Liquid Phas | 被引量 : 0次 | 上传用户:sandybobo
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
UHPLC methods at pressures up to 1500 bar can generate substantial heat in columns.A well known consequence is radial heterogeneity of the temperature in the column and the related loss of separation efficiency.
其他文献
Hydrophilic interaction chromatography(HILIC) has attracted increasing attention in recent years.Intensive research has been conducted in the areas of HILIC separation mechanisms,column techniques and
会议
Metastasis is the cause of most cancer deaths in patients with solid tumors.Circulating tumor cells(CTCs) are cancer cells disseminated from primary or secondary tumors that circulate in blood and may
会议
Owing to improper use,slow degradation and bio-accumulation through the food web,organophosphorus pesticides(OPPs) have gradully become a risk and threat to both humans and animals [1].In general,OPPs
会议
Glycoproteins are regulated in protein expression,glycosite occupancy,glycans,glycosite-specific glycans,and glycosite-specific glycan occupancy.Here,we report a comparative analysis of glycoproteins
会议
Comprehensive two-dimensional liquid chromatography(LC×LC) is a crucial technique for the separation of very complex samples of non-volatile molecules and it is virtually indispensable for the separat
会议
Hypertension and hyperlipidaemia are major risk factors for the development of atherosclerosis.Calcium channel blockers(CCBs) have been used for decades and have established antihypertensive effects.
会议
The introduction of HPLC particles with a non-porous core surrounded by a porous shell [1] has initiated intensive research for the reason of the extreme high separation efficiency of these particles.
会议
Abnormal lipid metabolism is a common feature in most solid tumours,which occurs in early stage of the tumour progression [1].
会议
Various approaches for evaluating and comparing the separation power of different HPLC and UHPLC sorbents have been used over the years such as Van Deemter,Poppe and Kinetic plots.
会议
In recent years,superficially porous particles have drawn great interest because of their special characteristics and improvement in separation efficiency.
会议