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5. Fingolimod depending on S1PR3 protects astrocytes against ischemia-induced neuroinflammative injury

Fingolimod depending on S1PR3 protects astrocytes against ischemia-induced neuroinflammative injury

来源 :中国药理学会北美分会药理学学术大会 | 被引量 : 0次 | 上传用户：laurachenqh

【摘 要】

：

　　Sphingosine-1-phosphate receptors(S1PRs)regulate multiple cellular functions such as proliferation,immunomodulation and apoptosis.Fingolimod(FTY720),a S1P r

【作 者】

：

Yin-feng DONG Zheng-zhen CHEN Dan-dan YANG Zhan ZHAO Juan JI Xiu-lan SUN 

【机 构】

：

Neuroprotective Drug Discovery Center,Jiangsu Key Laboratory of Neurodegeneration,Department of Phar

【出 处】

：

中国药理学会北美分会药理学学术大会

【发表日期】

：

2017年期

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论文部分内容阅读

　　Sphingosine-1-phosphate receptors(S1PRs)regulate multiple cellular functions such as proliferation,immunomodulation and apoptosis.Fingolimod(FTY720),a S1P receptor(S1PR1)agonist,is used as immunomodulatory therapy for multiple sclerosis.

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