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  5. LOW ENERGY ELECTRONS EMITTED BY 60-keV IRRADIATION OF GOLD NANOPARTICLES AND DNA DAMAGE

LOW ENERGY ELECTRONS EMITTED BY 60-keV IRRADIATION OF GOLD NANOPARTICLES AND DNA DAMAGE

来源 :中国微米纳米技术学会纳米科学技术分会第四届年会暨2016国际纳米生物与医学学术会议 | 被引量 : 0次 | 上传用户：zhouxifengli
【摘 要】
：
The potential application of gold nanoparticles(GNPs)as radiosensitizers in cancer radiotherapy attracts considerate interest.1 According to calculations,2 radiosensitization occurs mostly via the dam
【作 者】
：
Yanfang Dong Limei Zhou Qinfen Tian Yi Zheng Léon Sanche 
【机 构】
：
Research Institute of Photocatalysis,State Key Laboratory of Photocatalysis on Energy and Environmen
【出 处】
：
中国微米纳米技术学会纳米科学技术分会第四届年会暨2016国际纳米生物与医学学术会议
【发表日期】
：
2016年5期
【关键词】
：
Gold nanoparticle low-energy electrons DNA damage radiosensitization radiation 
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　　The potential application of gold nanoparticles(GNPs)as radiosensitizers in cancer radiotherapy attracts considerate interest.1 According to calculations,2 radiosensitization occurs mostly via the damage induced by additional secondary electrons(SEs)emitted from the GNPs upon irradiation by high energy particles or photons.In this study,we test this hypothesis experimentally and give an estimate of the range of most SEs.Naked GNPs and GNPs coated either with thiolated undecane(S-C11H23),or dithiolated diethylenetriaminepentaacetic(DTDTPA)chelating agents,were synthesized.
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