Kctd10 regulates heart morphogenesis by repressing the trans-activity of Tbx5

来源 :2012全国发育生物学大会 | 被引量 : 0次 | 上传用户:zhangyong131420
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  T-box (Tbx) transcription factors play essential roles in cardiac development in vertebrate.In particular, Tbx5 is the key regulator for the formation of cardiac chambers.Tbx5 is a dosage-dependent transcription factor, so it must be accurately regulated.
其他文献
会议
会议
会议
会议
会议
会议
Foxc1a, a fork head transcription factor, has been shown to be required for vertebrate somitogenesis.However, little is known about the molecular mechanism offoxc1a in myogenesis.Knocking down foxc1a,
会议
Wolbachia are obligate endosymbiotic bacteria that infect numerous species of arthropods and nematodes.Wolbachia can induce several reproductive phenotypes in their insect hosts, such as Cytoplasmic i
会议
The Roof plate-specific spondin 3 (RSPO3) plays crucial roles during embryogenesis by promoting Wnt/β-catenin signaling pathway in amphibian and mammals.However, the role of Rspo3 in other vertebrate
会议
Fibronectin and Laminin are the principal components of extracellular matrix, and the assembly into fibrils to form basement membrane is required for cell migration.In embryos, the assembly of Fibrone
会议