Investigation molecular dissolution mechanism of ketoprofen ternary solid dispersions by molecular d

来源 :中国化学会第14 届全国计算(机)化学学术会议暨分子模拟国际论坛 | 被引量 : 0次 | 上传用户：jtzou

【摘要】

：

　　[Introduction] Ketoprofen(KET)is a poorly-water soluble drug.To improve the solubility and dissolution rate of ketoprofen,previous experiments developed KET

【作者】

：

Weijie Chen Defang Ouyang

【机构】

：

StateKeyLaboratoryofQualityResearchinChineseMedicine,InstituteofChineseMedicalSciences(ICMS),Univers

【出处】

：

中国化学会第14 届全国计算(机)化学学术会议暨分子模拟国际论坛

【发表日期】

：

2017年11期

【关键词】

：

Ketoprofen Surfactans Solid Dispersion Molecular dynamics Dissolution molecular

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　　[Introduction] Ketoprofen(KET)is a poorly-water soluble drug.To improve the solubility and dissolution rate of ketoprofen,previous experiments developed KET-Polyethylene Glycol(PEG)-Tween 60(TWE)and KET-PEG-Sodium Dodecyl Sulfate(SDS)ternary solid dispersion.

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Investigation molecular dissolution mechanism of ketoprofen ternary solid dispersions by molecular d

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