The friction and third body wear behaviors of surface strengthened titanium alloy(TA2) were experimentally studied under air condition. The uniform simulated lunar soil particles was employed as the third body in the friction pair. For comparison, ultrasonic surface rolling technology and plasma nitriding were also used to investigate the effect of particles on surface topography and wear mechanism. Microstructure,features of particles and various sections in the worn surface layer, were systematically characterized by using X-ray diffraction (XRD) analysis, scanning electron microscopy (SEM) and energy dispersive X-ray spectrum (EDS). The test results indicate that the friction coefficient decrease significantly when there is a large n mber of particles. Which is resulted from the formation of granular deposition film and the rolling between particles. The friction coefficient improve slightly when the third body starts to adhering to the first body. Under the normal stress conditions, the furrows are taken on the friction surfaces and the friction coefficient increase severely. The primary wear c mechanism is abrasive wear. Moreover,the mosaic effect and micro-cutting action of third body microscopic particles increased fatigue wear of titanium alloy. All of the results propose that the tribological behaviors of nitrided titanium were significantly affected by third body particles. Also, the wear rate of the second body affect by the strengthen of the first body under the condition of the particles. This paper provides a general view of the contact situation of third body particles against surface strengthened titanium alloy,with special emphasis on morphology for grinding balls and wear mechanism of first integrated material.