【摘 要】
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Japanese encephalitis virus (JEV) is an arbovirus belonging to the family Flaviviridae,which can cause acute viral encephalitis in both humans and animals.Viperin (also known as cig5 and RSAD2),an ant
【机 构】
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State Key Laboratory of Virology,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan,Hubei
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Japanese encephalitis virus (JEV) is an arbovirus belonging to the family Flaviviridae,which can cause acute viral encephalitis in both humans and animals.Viperin (also known as cig5 and RSAD2),an antiviral protein induced by interferon,was identified originally in human megalomaniacs (HCMV) infected human fibroblasts.And it has been reported to have the ability to limit a broad range of viruses,such as Hepatitis C virus (HCV)、 dengue virus type-2 (DENV-2)、Chikungunya virus (CHIKV) and so on.
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