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目的分析胺碘酮治疗急性心肌梗死后室性心律失常的临床应用效果。方法选择2013年1月—2015年1月收治的室性心律失常患者70例作为研究对象,随机分为参照组和研究组各35例。参照组使用利多卡因进行治疗,研究组使用胺碘酮治疗。记录并比较两组PR间期、QRS波时限及室性心律失常发生次数,观察两组临床疗效。计量资料采用t检验,计数资料采用χ2检验,P<0.05为差异有统计学意义。结果研究组治疗总有效率为91.43%,显著高于参照组的60.00%,差异有统计学意义(P<0.05)。研究组室性心律失常发生次数、QRS波时限、PR间期分别为(910.31±102.31)次、(0.070±0.005)、(0.153±0.002)s,均优于参照组的(1 106.13±154.26)次、(0.088±0.007)、(0.142±0.002),差异均有统计学意义(均P<0.05)。结论胺碘酮治疗急性心肌梗死后室性心律失常临床疗效显著,有效率高,值得临床推广应用。
Objective To analyze the clinical effect of amiodarone in the treatment of ventricular arrhythmias after acute myocardial infarction. Methods Seventy patients with ventricular arrhythmia admitted from January 2013 to January 2015 were selected as study subjects and randomly divided into reference group (35 cases) and study group (35 cases). The reference group was treated with lidocaine, and the study group was treated with amiodarone. Record and compare PR interval, QRS wave duration and incidence of ventricular arrhythmia, and observe the clinical curative effect of the two groups. Measurement data using t test, count data using χ2 test, P <0.05 for the difference was statistically significant. Results The total effective rate of the study group was 91.43%, which was significantly higher than that of the reference group (60.00%), the difference was statistically significant (P <0.05). The number of ventricular arrhythmia, QRS wave duration and PR interval in the study group were (910.31 ± 102.31), (0.070 ± 0.005) and (0.153 ± 0.002) s, respectively, which were better than that of the reference group (106.13 ± 154.26) (0.088 ± 0.007) and (0.142 ± 0.002) respectively, all of which were statistically significant (all P <0.05). Conclusions Amiodarone is effective in treating ventricular arrhythmia after acute myocardial infarction and its clinical application is worthy of clinical application.