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急性间质性肾炎包括四种类型,即急性细菌性肾盂肾炎、急性药物过敏间质肾炎、感染性急性间质性肾炎,急性特发性间质性肾炎。以前两种为常见。药物性急性过敏反应性间质性肾炎是急性肾衰的一个重要原因。引起急性间质性肾炎的药物达50余种。大量文献资料报道主要是B—内酰胺类抗生素(包括青霉素G、新型青霉素Ⅰ、氨基苄青霉素、新型青霉素Ⅱ、新型青霉素Ⅲ、羧苄青霉素、羟氨苄青霉素、先锋霉素Ⅰ、先锋霉素Ⅳ、先锋霉素Ⅱ、头孢氨噻肟、先锋霉素Ⅴ);其它抗生素有磺胺类及复方新诺明、利福平、四环素、万古霉素、红霉素,非类固醇抗炎药:消炎痛、保太松、布洛芬、
Acute interstitial nephritis include four types, namely acute bacterial pyelonephritis, acute drug allergy interstitial nephritis, acute interstitial nephritis infection, acute idiopathic interstitial nephritis. The previous two are common. Drug-induced acute allergic interstitial nephritis is an important cause of acute renal failure. Acute interstitial nephritis caused by up to 50 kinds of drugs. A large number of literature reports mainly B-lactam antibiotics (including penicillin G, new penicillin Ⅰ, ampicillin, new penicillin Ⅱ, new penicillin Ⅲ, carbenicillin, amoxicillin, cephamycin Ⅰ, cephalosporin Ⅳ , Cephalosporin, cefotaxime, cephalosporin Ⅴ); other antibiotics sulfonamides and cotrimoxazole, rifampin, tetracycline, vancomycin, erythromycin, non-steroidal anti-inflammatory drugs: indomethacin , Paul too loose, ibuprofen,