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目的:探讨分析阿奇霉素联合盐酸氨溴索治疗儿童哮喘急性发作期的效果和安全性。方法:将儿童哮喘患者轻度发作患者68例纳入为本次研究工作对象,并依据患者收治入院时间分为两组,对照组患者除基础治疗外采用阿奇霉素治疗,研究组则除基础治疗外应用阿奇霉素联合盐酸氨溴索治疗。结果:研究组的临床总有效率(97.06%)显著优于对照组(70.59%),P<0.05;研究组的体征及症状消失时间及住均院时间显著优于对照组,P<0.05;研究组的不良反应发生率(2.94%)与对照组(5.88%),P>0.05。结论:阿奇霉素联合盐酸氨溴索治疗儿童哮喘急性发作的效果显著,且安全性较高,值得临床推广及加强应用。
Objective: To investigate the efficacy and safety of azithromycin combined with ambroxol hydrochloride in the treatment of acute exacerbation of childhood asthma. Methods: Sixty-eight children with mild asthma exacerbation were enrolled in this study. The patients were divided into two groups according to the hospital admission time. The patients in the control group were treated with azithromycin except for the basic treatment and the study group was treated with basic therapy Azithromycin combined with ambroxol hydrochloride treatment. Results: The total effective rate (97.06%) in the study group was significantly better than that in the control group (70.59%) (P <0.05). The signs and symptom disappearance time and hospital stay in the study group were significantly better than those in the control group (P <0.05) The incidence of adverse reactions in the study group (2.94%) and control group (5.88%), P> 0.05. Conclusion: Azithromycin combined with ambroxol hydrochloride in children with acute attack of asthma significant effect, and high safety, worthy of clinical promotion and strengthen the application.