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作者应用自行设计和研制的自动微量脉冲输液泵,采用国产黄体生成素释放激素(LHRH)皮下脉冲输注,治疗下丘脑性闭经和多囊卵巢综合征患者。给药方法为每隔90分钟释液50μl(含LH-RH15～20μg)1次,每次1分钟。1例下丘脑闭经经治疗后,于第1治疗周期即有排卵,血牢FSH、LH、E_2和孕酮等均达到正常水平。1例多囊综合征经治疗49天无效,行卵巢楔形切除术后2月,基础体温出现双相,排卵转经。文内对给药的剂量、频率和途径等进行了讨论。
Authors designed and developed by the application of automatic micro-pulse infusion pump, the use of domestic luteinizing hormone-releasing hormone (LHRH) subcutaneous pulse infusion, treatment of patients with hypothalamic amenorrhea and polycystic ovary syndrome. The method of administration is to dispense 50 μl (containing LH-RH 15 to 20 μg) once every 90 minutes for 1 minute each. One case of hypothalamic amenorrhea after treatment, in the first cycle of treatment that has ovulation, blood-fast FSH, LH, E_2 and progesterone, etc. reached the normal level. One case of polycystic syndrome after 49 days of treatment is invalid, ovarian wedge resection in February, basal body temperature appeared biphasic, ovulation and menstruation. The dosage, frequency and route of administration are discussed in the article.