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过去十年在应用许多合成或非合成移植物治疗大面积腹壁缺损中已涌现出多种方法。最为有效的是1965年报道的Marlex(聚丙烯)移植物,并已获得广泛应用。然而,此法有并发症,多数是与其在人体组织内成为异物有关。再者,它掺入周围组织不是天衣无缝,在切口疝修补术中约发生50%切口并发症,和10.2%复发率,这提出需要更好的移植物。 1955年Naral研究院采用冰冻的干硬脑膜同种移植物,经过去20年的大量研究揭示了这种移植物的特殊性质。根据这些资料,作者用以修补4例腹壁大面积缺损。动物实验结果证实,尸体的硬脑膜经干燥冷冻和复温后,保持其原有的强度,无免疫学活性,受体极易耐受,并与受体的脑膜渗合。长达15年的随访证
A number of methods have emerged in the past decade in the treatment of extensive abdominal wall defects using many synthetic or non-synthetic grafts. The most effective is the Marlex (polypropylene) graft reported in 1965 and has gained widespread use. However, this method has complications, most of which are related to its foreign body in the human body. Again, its incorporation into the surrounding tissue is not as seamless as 50% of incisional complications and 10.2% of recurrence rates in incisional hernia repair, suggesting the need for better grafts. Naral Institute in 1955 using frozen dural allografts, after 20 years of extensive research revealed the special nature of this graft. Based on these data, the authors used to repair 4 cases of extensive abdominal wall defects. Animal experiments confirmed that the body of the dura after drying and freezing and rewarming, to maintain its original strength, non-immunological activity, the receptor is very easy to tolerate, and with the receptor of the meninges. Up to 15 years of follow-up card