应用碱裂解加溶菌酶法对本地区１９９６ 年分离鉴定的１５５ 株标本进行了质粒抽提及质粒谱分型研究。结果表明：５种不同分子量的质粒分别被检出，其中分子量为５３４６ 和３９５ｋｂ 两种质粒检出率较高，分别为９６１３ ％ 和９０３２ ％ 。质粒谱型共１０ 种，主要以２１ｋｂ ＋ ５３ｋｂ ＋ ３９５ｋｂ 和２１ｋｂ ＋４２ｋｂ＋ ５３ｋｂ ＋ ７４ｋｂ ＋ ３９５ｋｂ 为主，占６３５８ ％ （９６／１５１） 。并将耐药谱型与质粒谱型进行了比较，具有相同质粒谱型的菌株，其耐药谱型可相同亦可不同。并地淋病奈瑟菌质粒抽提方法进行了探讨，摸索出了一种快速质粒检测的简便方法。 155 samples isolated and identified in 1996 in this area were subjected to plasmid extraction and plasmid profiling using alkaline lysis plus lysozyme. The results showed that five kinds of plasmids with different molecular weights were detected respectively. The detection rates of the two plasmids with molecular weights of 5346 and 395kb were 9613% and 9032% respectively. There were 10 plasmids in total, accounting for 6358% (21kb + 53kb + 395kb and 21kb + 42kb + 53kb + 74kb + 395kb respectively) ). The resistant spectrum and the plasmid profile were compared. The strains with the same plasmid profile could be the same or different. And to Neisseria gonorrhoeae plasmid extraction methods were explored, to explore a quick and easy plasmid detection method.