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作者报告一例女性患者,35岁(1971年)时,因发热、面部及躯干皮损、关节炎、肾病、高血压和贫血被诊断为SLE。1972年肾活检作免疫荧光检查于肾小球基底膜处有颗粒型荧光。治疗用强的松60mg/d,维持剂量15mg/d。1977年2月28日突然发生心肌梗塞送至医院已低血压休克,翌日心跳停止死亡。死后17小时作尸解,发现右冠状动脉完全梗塞,左冠状动脉变窄,左心尖处有一动脉瘤,切片见动脉瘤壁附近心肌坏死、出血。肾脏有局灶节段性增殖性肾小球肾炎及纤维变性,小动脉硬化、纤维样变性和洋葱圈样结构。尸解诊断:SLE、狼疮性肾炎、重度动脉硬化性心脏病伴有①冠状动脉严重
The authors report a female patient, 35 years old (1971), diagnosed with SLE due to fever, facial and torso lesions, arthritis, kidney disease, hypertension and anemia. Renal biopsy in 1972 for immunofluorescence at the glomerular basement membrane granular fluorescence. Treatment with prednisone 60mg / d, maintenance dose 15mg / d. February 28, 1977 sudden myocardial infarction was sent to the hospital has been hypotensive shock, the heart the next day to stop death. 17 hours after death for autopsy and found complete right coronary artery infarction, left coronary artery narrowing, left apex at an aneurysm, see the aneurysm wall near the myocardial necrosis, bleeding. Kidney has focal segmental proliferative glomerulonephritis and fibrosis, arteriosclerosis, fibrosis and onion ring-like structure. Autopsy diagnosis: SLE, lupus nephritis, severe arteriosclerotic heart disease associated with severe ① coronary artery