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迷宫术是手术治疗房颤的标准方法,它的长期治愈率超过90%.但由于手术的复杂性和术后严重并发症等原因,其应用受到很大限制. 方法选用6只Hanford小种猪,体重40～50kg,术前行磁共振成像(MRI)检查,以评价(1)全心功能;(2)二尖瓣和三尖瓣功能;(3)肺静脉结构和血流;(4)冠脉结构和血流.术中取胸骨正中切口.暂时结扎左、右肺静脉和下腔静脉.隔离左、右肺静脉区,使心跳冲动来源于右心耳.术中静脉注射肝素(350U/kg),保持活性凝血时间>250s.制作迷宫过程中采用双极射频消融装置.
Maze is the standard method of surgical treatment of atrial fibrillation, its long-term cure rate of more than 90%, but due to the complexity of the operation and postoperative serious complications and other reasons, its application is greatly limited.Methods Six Hanford small pigs, Weight 40 ~ 50kg, preoperative magnetic resonance imaging (MRI) examination to evaluate (1) cardiac function; (2) mitral and tricuspid valve function; (3) pulmonary vein structure and blood flow; Vein structure and blood flow, the midline sternotomy was performed intraoperatively, the left and right pulmonary veins and inferior vena cava were temporarily ligated, the left and right pulmonary vein areas were isolated, and the impulse of heartbeat originated from the right atrial appendage. Intraoperative heparin (350U / kg) Maintaining active clotting time> 250s. Bipolar radiofrequency ablation device is used in the maze making process.