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6例狼疮性肾炎患者,其临床表现均限于:水肿、蛋白尿、血尿、管型尿、血清白蛋白水平降低、不同程度的氮质血症、内生肌酐清除率下降,以及贫血、血沉加速、血压升高等。特殊检查除血清抗核抗体(ANA)阳性(滴度:2例1:80,4例1:40)外,余反复测定均为阴性(包括红斑狼疮细胞试验、抗DNA抗体、抗ENA抗体和溶血性补体水平等)。肾组织活检证实为程度不同的局灶型或弥漫型增生性肾小球肾炎。在一组53例典型SLE病人作正常皮肤检查免疫荧光,26例阳性,而另一组非狼疮肾病者全部阴性。因此作者用免疫萤光法检查肾组织标本和非
Six patients with lupus nephritis, its clinical manifestations were limited to: edema, proteinuria, hematuria, tubular urine, serum albumin levels decreased, varying degrees of azotemia, decreased creatinine clearance, and anemia, ESR acceleration , High blood pressure and so on. Special tests were repeated except for the positive ANA (titers: 1 in 2 cases and 4 in 1 case, 40 cases in 1:40 cases) (including lupus erythematosus cell test, anti-DNA antibody, anti-ENA antibody and Hemolytic complement level, etc.). Kidney biopsy confirmed the degree of different focal or diffuse proliferative glomerulonephritis. In a group of 53 patients with typical SLE normal skin immunofluorescence examination, 26 cases were positive, while the other group of non-lupus nephropathy were all negative. Therefore, the authors used immunofluorescence to examine renal tissue specimens and non-tumor tissues