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《New Engl J Med》1985,312(123):1515,June 6。过去十年中,曾报告过许多新奇的感染性疾病,引起了公众的注意。以往对这种感染有种种推测,现已表明此为δ肝炎病毒所致。肝炎δ病毒具有独特的混合结构,其中心为δ核,外层包裹着乙型肝炎表面抗原。肝炎δ病毒是有缺陷的RNA病毒,本身不能单独存活,需要DNA病毒,即乙型肝炎病毒(或其他肝炎病毒)的辅助,才能复制和表达。所以,肝炎δ病毒仅能感染患有乙型肝炎的病人;
New Engl J Med 1985, 312 (123): 1515, June 6. In the past decade, many novel infectious diseases have been reported and have drawn the public’s attention. In the past there are many speculations about this infection, it has been shown that this is due to hepatitis virus. Hepatitis delta virus has a unique mixed structure, the center of the δ core, the outer layer wrapped with hepatitis B surface antigen. The hepatitis delta virus is a defective RNA virus that itself can not survive alone and requires the help of the DNA virus, the Hepatitis B virus (or other hepatitis virus), to replicate and express. Therefore, hepatitis delta virus can only infect patients with hepatitis B;