论文部分内容阅读
目的:探讨布地奈德吸入治疗慢性阻塞性肺疾病急性发作的疗效。方法:慢性阻塞性肺疾病急性发作患者28例随机分为治疗组15例和对照组13例,对照组给予常规治疗,治疗组在常规治疗基础上加用布地奈德混悬液1 mg氧气驱动雾化吸入,4次/d,5～10 min/次,疗程5～7 d。比较2组疗效,第1秒用力呼气容积、用力肺活量、峰值呼气流速、动脉血氧分压、动脉血二氧化碳分压改善情况。结果:治疗组疗效优于对照组(P<0.05),第1秒用力呼气容积、用力肺活量、峰值呼气流速、动脉血氧分压、动脉血二氧化碳分压改善优于对照组(P<0.05)。结论:布地奈德吸入治疗可作为口服糖皮质激素的替代或辅助用药。
Objective: To investigate the efficacy of budesonide inhalation in the treatment of acute exacerbation of chronic obstructive pulmonary disease. Methods: A total of 28 patients with acute COPD were randomly divided into treatment group (n = 15) and control group (n = 13). The control group was given routine treatment. The treatment group was given budesonide suspension 1 mg oxygen on the basis of routine treatment Inhalation inhalation, 4 times / d, 5 ~ 10 min / time, treatment of 5 ~ 7 d. Comparison of two groups, the first second forced expiratory volume, forced vital capacity, peak expiratory flow, arterial partial pressure of oxygen, arterial partial pressure of carbon dioxide to improve the situation. Results: The curative effect in the treatment group was better than that in the control group (P <0.05), and forced expiratory volume in 1 second, forced vital capacity, peak expiratory flow rate, arterial partial pressure of oxygen and partial pressure of arterial carbon dioxide were improved better than those in control group (P < 0.05). Conclusion: Budesonide inhalation therapy can be used as an alternative or adjuvant to oral glucocorticoids.