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目的:探讨复方磺胺甲恶唑联合常规雾化治疗支气管结核的效果。方法:将90例痰涂片阳性的支气管结核患者(男29例,女61例)依据随机、对照、双盲的原则分为治疗组和对照组,每组45例。对照组予以常规雾化治疗,治疗组予以常规雾化联合复方磺胺甲恶唑口服。对两组患者的治疗效果(症状缓解、痰菌转阴、病变好转)以及治疗期间的安全性进行比较。结果:治疗组的临床疗效优于对照组(P<0.01),两组治疗有效率差异有统计学意义(P<0.05)。结论:复方磺胺甲恶唑联合常规雾化治疗可明显改善支气管结核痰涂阳性患者的临床症状,提高痰菌转阴率,治疗总有效率较高且安全可靠。
Objective: To investigate the effect of compound sulfamethoxazole combined with conventional atomization on bronchial tuberculosis. Methods: 90 cases of sputum smear-positive bronchial tuberculosis patients (29 males and 61 females) were divided into treatment group and control group according to the principle of randomized, controlled and double-blind, with 45 cases in each group. The control group was given conventional nebulization, and the treatment group was given routine nebulization combined with compound sulfamethoxazole. The efficacy of treatment (symptomatic relief, sputum negative conversion, improvement of disease) and safety during treatment were compared between the two groups. Results: The clinical efficacy of the treatment group was better than that of the control group (P <0.01). There was significant difference between the two groups in the treatment efficiency (P <0.05). Conclusion: Compound sulfamethoxazole combined with conventional atomization therapy can significantly improve the clinical symptoms of sputum smear positive patients with bronchial tuberculosis and improve the negative rate of sputum bacteria. The total effective rate is high and safe and reliable.