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将花生四烯酸激活的血小板加入兔主动脉条浴槽液中引起动脉条明显收缩。苯海拉明，ＴＸＡ２受体阻断剂或３，４’，５－三羟基芪－３－β－单－Ｄ－葡萄糖甙（Ｐｏｌ）均可减弱此种收缩作用，以苯海拉明效价最高，提示此血管条收缩主要归因于血小板释放的组胺，其次为ＴＸＡ２；Ｐｏｌｌ．４×１０－３ｍｏｌ／Ｌ及４．２×１０－３ｍｏｌ／Ｌ有显著抑制血小板诱导主动脉条的收缩作用。Ｐｏｌ使组胺收缩血管条量效曲线不平行右移，效能下降，具有非竞争性抑制组胺收缩血管作用。
Arachidonic acid activated platelets added to the aortic strips bath caused aortic contraction significantly. Diphenhydramine, TXA2 receptor blockers or 3,4 ’, 5-trihydroxystilbene-3-β-glucoside (Pol) can reduce this contractile effect with diphenhydramine effect The highest price suggested that the contraction of the vascular strips was mainly attributed to platelet-released histamine, followed by TXA2; Poll. 4 × 10-3mol / L and 4.2 × 10-3mol / L significantly inhibited platelet-induced contraction of aortic strips. Pol causes histamine contraction of vascular volume and effect curve is not parallel to the right shift, the performance decline, with non-competitive inhibition of histamine contraction of blood vessels.