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报道了以肉桂酸（１）为起始原料，经混酐化、酰化、Ｄｏｅｂｎｅｒ等三步反应制得关键中间体３－［３－甲氧基－４－（３－苯丙烯酰基）氧基］苯基丙烯酸（４）。其与对甲基苯磺酰氯形成混酐或在ＤＣＣ和ＤＭＡＰ系统催化下分别与苯甲醇、肉桂醇、２－萘酚、对羟基苯乙酸反应成酯。所合成的标题化合物均经元素分析、红外光谱和核磁共振氢谱确证结构与构型。
The key intermediate 3- [3-methoxy-4- (3-phenylpropenoyl) oxy) -butyric acid was prepared by cinnamic acid (1) Phenyl] acrylic acid (4). It is mixed with p-methylbenzenesulfonyl chloride to form mixed anhydride or reacted with benzyl alcohol, cinnamyl alcohol, 2-naphthol and p-hydroxyphenylacetic acid respectively under the catalysis of DCC and DMAP system to form ester. The title compounds were synthesized by elemental analysis, IR and 1H-NMR confirmed the structure and configuration.