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目的:观察中西医结合治疗强直性脊柱炎的临床疗效。方法:采用随机平行对照试验设计,将107例强直性脊柱炎患者平均分为两组。治疗组常规西药治疗联合中药汤剂内服,对照组采用常规西药治疗,两组均以30d为1疗程。比较两组间及治疗前后活动性指数(BASDAI)、功能性指数(BASFI)、晨僵时间,比较两组的有效率,观察不良反应的发生情况。结果:两组在改善关节疼痛、功能受损情况及僵硬等方面均有较好疗效,与治疗前比较,差异均有统计学意义(P<0.05),且治疗组均优于对照组,差异有统计学意义(P<0.05);两组有效率比较,差异无统计学意义,但治疗组的有效率明显较对照组高。结论:中西医结合治疗强直性脊柱炎疗效确切,不良反应少,值得临床推广。
Objective: To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of ankylosing spondylitis. Methods: A randomized controlled trial was designed to divide 107 patients with ankylosing spondylitis into two groups. In the treatment group, conventional western medicine combined with Chinese medicine decoction was administered orally, while in the control group, conventional western medicine was used for treatment. Both groups were treated with 30 days for 1 course of treatment. The BASDAI, BASFI and morning stiffness were compared between the two groups before and after treatment. The effective rate of the two groups was compared to observe the incidence of adverse reactions. Results: The two groups had better curative effect in improving joint pain, impaired function and stiffness, compared with those before treatment, the difference was statistically significant (P <0.05), and the treatment group were better than the control group, the difference was statistically significant (P <0.05). There was no significant difference between the two groups in the effective rate, but the effective rate in the treatment group was significantly higher than that in the control group. Conclusion: The treatment of ankylosing spondylitis with integrated traditional Chinese and western medicine has definite curative effect and few adverse reactions, which deserves clinical promotion.