糖尿病严重细菌性足部感染患者需要适当的抗生素治疗和外科干预。磷霉素分子量小、不与血浆蛋白结合,因此在细胞间液和软组织的渗透性好。且磷霉素与羟磷灰石结构相近,故能与骨组织结合。 Patients with severe bacterial foot infections in diabetes require appropriate antibiotic therapy and surgical intervention. Fosomycin has a low molecular weight and does not bind to plasma proteins. Therefore, fosfomycin has good permeability in the interstitial fluid and soft tissue. And fosfomycin and hydroxyapatite structure similar, it can be combined with bone tissue.