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作者报道5例青少年病人服用四环素类药物后造成食管炎。病人5例,年龄15～20岁,男2例,女3例。3例服用四环素,2例服用强力毒素、脱氧土霉素后的第1天至第3周中出现了严重的吞咽困难和胸骨柄下疼痛。5例病人均在晚上睡前服药,当时饮水很少或不饮水干咽药片。出现症状后,做食管内窥镜检查发现中段食管炎1例、末端食管炎1例。组织学检查显示食管内壁有溃疡伴有急慢性炎症。5
The authors report that 5 cases of young patients taking tetracycline drugs cause esophagitis. 5 patients, aged 15 to 20 years old, 2 males and 3 females. Three patients who took tetracycline and two who took powerful toxins developed severe dysphagia and sore thighs during the first day to the third week after deoxytetracycline treatment. 5 patients took medication at bedtime at night, when drinking little or no water pharynx tablets. After symptoms, do esophageal endoscopy found middle esophagitis in 1 case, end esophagitis in 1 case. Histological examination showed that the inner wall of the esophagus with ulcer accompanied by acute and chronic inflammation. 5