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胎膜早破的病因主要有:生殖道感染、羊膜腔内压力增高、羊水过多、胎位异常、宫颈内口松弛及胎膜发育异常等。胎膜早破可导致孕妇感染和胎盘早剥,以及胎儿早产、感染、脐带脱垂等并发症。临床上用宫缩抑制剂治疗未足月胎膜早破(PPROM)以延长孕周提高围产儿存活率,因治疗同时也有发生宫内感染、胎儿宫内窘迫等,宫缩抑制剂的使用还存在有不同看法。
The main causes of premature rupture of membranes are: reproductive tract infections, increased pressure in the amniotic cavity, polyhydramnios, abnormal fetal position, cervix, mouth relaxation and abnormal fetal membranes and so on. Premature rupture of membranes can lead to maternal infection and placental abruption, as well as fetal premature birth, infection, umbilical cord prolapse and other complications. The clinical use of tocolytic agents for treatment of unexplained premature rupture of membranes (PPROM) to prolong the gestational age to improve perinatal survival, due to the treatment of intrauterine infection, fetal distress, etc., the use of tocolytic also There are different views.