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目的观察硫酸镁治疗妊娠高血压综合征患者血液流变性的变化及临床效果。方法 57例妊娠高血压综合征患者给予硫酸镁治疗,比较治疗前后患者血液流变学各项指标的变化情况,并与正常妊娠对比分析。结果妊娠高血压综合征治疗组血液流变学各项指标与正常妊娠组比较均有明显差异(P<0.05);治疗组治疗后血流变学各项指标均较治疗前红细胞压积、血浆黏度、全血还原黏度等显著降低(P<0.01),其余项目也有明显下降(P<0.05),差异均有统计学意义。结论硫酸镁治疗妊娠高血压综合征可明显降低血液流变性,改善微循环。
Objective To observe the change and clinical effect of magnesium sulfate on hemorheology in patients with pregnancy induced hypertension. Methods Fifty-seven patients with pregnancy-induced hypertension were treated with magnesium sulfate. The changes of hemorheology indexes before and after treatment were compared with those of normal pregnancy. Results The indexes of hemorrheology in pregnancy-induced hypertension syndrome group were significantly different from those in normal pregnancy group (P <0.05). The indexes of hemorheology in treatment group were significantly higher than those before treatment in terms of hematocrit, plasma Viscosity, reduction of whole blood viscosity and other significantly reduced (P <0.01), the remaining items also decreased significantly (P <0.05), the differences were statistically significant. Conclusion Magnesium sulfate treatment of pregnancy-induced hypertension can significantly reduce hemorrheology and improve microcirculation.