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Objective:To evaluate potential memory enhancing effect of Punica granatum peel extract on rats.Methods:Healthy adult male albino rats of Wistar strain were used.Each group of 6 rats were administered either distilled water or 50 mg/kg of extract or 100 mg/kg of extract for 15 days and subjected to passive avoidance test or T-maze test.In the next phase rats were administered distilled water or 100 mg/kg of extract for 15 days and the rats were given injection diazepam before subjecting them to the tests.Results:The overall performance was better in test groups compared to control groups.Among the test groups,100 mg/kg rats performed better than 50 mg/kg.The effect on spatial learning parameters like mean number of alternations and mean percentage bias was more marked compared to retention testing parameters like latency. 100 mg/kg Punica extract treated group also improved performance of diazepam treated rats. Conclusions:There is a definite trend of memory improvement by Punica granatum peel with effects being more marked on spatial learning tendency and long term memory than on retention capacity.
Objective: To evaluate potential memory enhancing effect of Punica granatum peel extract on rats. Methods: Healthy adult male albino rats of Wistar strain were used. Each group of 6 rats were administered either distilled water or 50 mg / kg of extract or 100 mg / kg of extract for 15 days and subjected to passive avoidance test or T-maze test. the next phase rats were administered distilled water or 100 mg / kg of extract for 15 days and the rats were given injection diazepam before subjecting them to the tests Results: The overall performance was better in test groups compared to control groups. Among the test groups, 100 mg / kg rats performed better than 50 mg / kg. The effect on spatial learning parameters like mean number of alternations and mean percentage bias was more marked compared to retention testing parameters like latency. 100 mg / kg Punica extract treated group also improved performance of diazepam treated rats. Conclusions: There is a definite trend of memory improvement by Punica grana tum peel with effects being more marked on spatial learning tendency and long term memory than on retention capacity.