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探索超声生物测量用于产前筛查胎儿唐氏综合征的意义,用超声测量胎儿的双顶径、长骨、及颈项皮肤。建立各项指标的回归公式,对中期孕妇各项超声指标作评价,并计算风险率。共测量264例单胎孕妇,经计算9.4％的孕妇风险率大于正常截断值,需进一步作羊水检查。对2例已知唐氏综合征的胎儿,用同样的方法作风险率估计,结果,其风险率明显高于正常平均值。本项技术同样适合我国,并能成为一项操作简便且非损伤性的产前优生方法。
To explore the significance of ultrasound biopsy for prenatal screening for fetal Down Syndrome and to measure the fetus’s biparietal diameter, long bones, and neck skin with ultrasound. Establish the regression formula of each index, evaluate the ultrasound indexes of mid-term pregnant women, and calculate the risk rate. A total of 264 singleton pregnancies were measured. The risk of pregnant women was 9.4%. The risk of pregnancy was higher than the normal cutoff value, and further examination of amniotic fluid was needed. In the two fetuses with Down’s syndrome, the same method was used to estimate the risk. As a result, the risk was significantly higher than the normal average. This technology is also suitable for our country, and can become a simple and non-invasive method of prenatal eugenics.