心肌桥和壁冠状动脉的形态及相关性研究

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随机采用成年经福尔马林固定后的心100例(已去除明显血管病变者)。重点解剖左冠状动脉主要分支前室间支,观测心肌桥出现部位、宽度和厚度,取桥下段血管(壁冠状动脉)中份及出桥段血管起始部,作石蜡切片HE染色,在光镜和计算机图象分析仪下观察其断面形态,并测定血管内径、内膜及中膜厚度,对所得数据作统计学处理和相关分析。结果显示,前空间支心肌桥出现率为75%(75例),其中68例(90.7%)为单桥,仅有7例(9.2%)为双桥,心肌桥常见部位为前室间沟中1/3(76%)段。桥宽和桥厚分别为19.14±0.49mm和1.37±0.65mm。壁冠状动脉内径为1.55±057mm,中膜与内膜共厚015±007mm;出桥段血管起始部管径为1.86±051mm,中、内膜厚0.16±0.07mm。47例(64.8%)桥下段血管内径小于出桥段血管起始部内径。在光镜及图象处理仪下,可见部分壁冠状动脉管壁内陷,内膜厚薄不均,据断面的不同形态,将其分为圆形(38例,50.7%)、椭圆形(16例,ZI.3%)、心形(6例,8.0%)、不规则形(7例,9.3%)和线形(8例,10.7%)五类。管腔呈线形裂隙者,形态上近似闭塞。相关分析表明,心肌桥与出桥段血官起始部内径呈正相关(P200043)。本课题为心血管造影、心脏外科以及为阐明心肌桥对心 100 cases of formalin-fixed adult hearts were randomly selected (those with obvious vascular lesions removed). The anterior branch of the main branch of the left coronary artery was dissected and the location, width and thickness of the myocardial bridge were observed. The middle part of the bridge and the starting part of the vessel in the middle part of the bridge were taken for paraffin section HE staining. The morphology of the cross section was observed under a mirror and a computer image analyzer. The inner diameter of the blood vessel, the thickness of the intima and the media were measured, and the data were statistically processed and correlated. The results showed that the incidence of myocardial bridge in the anterior space was 75% (75 cases), of which 68 cases (90.7%) were single bridge, only 7 cases (9.2%) were double bridge, the common site of myocardial bridge was Anterior groove between the groove 1/3 (76%). Bridge width and bridge thickness were 19.14 ± 0.49mm and 1.37 ± 0.65mm respectively. The diameter of the wall coronary artery was 1.55 ± 057mm, the thickness of the medial and the intima were 015 ± 007mm; the diameter of the blood vessel at the beginning of the bridge was 1.86 ± 051mm, the thickness of the medial and intima was 0.16 ± 0.07mm . In 47 cases (64.8%), the diameter of the blood vessels in the lower part of the bridge was smaller than the diameter of the initial part of the blood vessels in the outlet segment. Under the light microscope and image processing instrument, some of the walls of the coronary arteries were invaginated and intima thickness was uneven. According to the different morphologies of the sections, they were divided into round (38 cases, 50.7%), oval (16 cases, ZI.3%), heart (6 cases, 8.0%), irregular shape (7 cases, 9.3%) and linear (8 cases, 10.7%). Lumens were linear cracks were morphologically similar occlusion. Correlation analysis showed that there was a positive correlation between the diameter of myocardial bridge and the diameter of the starting portion of the outlet bridge (P200043). The topic of cardiovascular angiography, cardiac surgery and to clarify the myocardial bridge on the heart
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