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抗EGFR单克隆抗体是治疗结肠癌的靶向药物,该抗体明确的结构确认,无论是开发还是研究都有重大意义。在对抗EGFR单克隆抗体检测过程中,异质性检测已经成为不可缺少的项目。本文通过离子交换色谱法对抗EGFR单克隆抗体进行异质性分析,为抗EGFR单克隆抗体检测提供新的方法和手段。
Anti-EGFR monoclonal antibody is a targeted drug for the treatment of colon cancer. The definite structural confirmation of this antibody is of great significance in both development and research. Heterogeneity testing has become an indispensable item in the testing of monoclonal antibodies against EGFR. In this paper, by ion exchange chromatography anti-EGFR monoclonal antibody heterogeneity analysis for anti-EGFR monoclonal antibody detection provides a new method and means.