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本文通过临床观察隐睾症儿童术前、术后血清中表皮生长因子 (EGF) ,睾酮 (T) ,5α 双氢睾酮 (5α DHT)的浓度变化和隐睾症的关系 ,以探讨EGF在隐睾发病中的作用和二者之间的关系。采用放射免疫法 (RIA)对 40例隐睾儿童术前、术后外周静脉血清EGF、T、5α DHT进行了测定 ,并与 2 4例正常儿童进行了比较。隐睾症儿童术前组血清EGF、T、5α DHT值明显低于正常儿童 ,而术后组血清EGF、T、5α DHT明显上升。隐睾症儿童血清EGF明显降低 ,可能是影响睾丸正常下降和正常发育的重要因素
In this paper, the clinical observation of cryptorchidism children preoperative and postoperative serum levels of epidermal growth factor (EGF), testosterone (T), 5α dihydrotestosterone (5α DHT) concentration and cryptorchidism in order to explore the EGF in hidden The role of testis and the relationship between the two. Radioimmunoassay (RIA) was used to measure the levels of EGF, T and 5α DHT in peripheral blood of 40 children with cryptorchidism before and after operation, and compared with 24 normal children. The serum levels of EGF, T and 5α DHT in pre-operation group were significantly lower than those in normal children, while the levels of EGF, T and 5α DHT in postoperative group were significantly increased. Cryptorchidism serum EGF was significantly lower, may affect the testicular normal decline and normal development of an important factor