本组30例,均来自农村,为旧法接生致脐带感染,并出现典型破伤风表现者。除常规应用T.A.T外,镇静剂限用安定,一般用1.5～5mg/kg/d,分3～4次肌注,病情严重者同时另用5mg加入10％葡萄糖100ml或250ml缓滴,要求患儿处于嗜睡状态,在刺激时能啼哭或发生短暂痉挛,但不致于发生严重抽搐。本组治愈18例,死亡12例,死亡率为40％。讨论:破伤风外毒素主要作用于脊髓前角运动细胞或神经肌肉运动终板,从而引起横纹肌痉挛。安定 The group of 30 cases, all from the rural areas, the umbilical cord infection caused by the old method of delivery, and typical tetanus performance. In addition to the routine use of TAT, the sedatives with diazepam, generally with 1.5 ~ 5mg / kg / d, 3 to 4 times intramuscular injection, in serious cases, while another 5mg added 10% glucose 100ml or 250ml slow drops, requiring children in Lethargy, crying or transient spasms while stimulating, but not causing severe convulsions. The group cured 18 cases, 12 patients died, the mortality rate was 40%. Discussion: Tetanus Exotoxin mainly acts on motor cells in the anterior horn of the spinal cord or neuromuscular motor endplates, causing striated muscle spasms. stable