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美《New Engl Med J》1982,306(10):605编辑部文章:在Henry Bence Jones发现多发性骨髓瘤病人中有不寻常热性能的尿蛋白后,Edelman及Gally证明这种奇怪的蛋白是免疫球蛋白分子的轻多肽蛋白(κ和λ链)巳过了一个多世纪.现巳知道,正常尿液中含有极少量多克隆来源的游离κ和λ轻链的混合
New Engl Med J, 1982, 306 (10): 605 Editorial Department: Edelman & Gally Show This Weird Protein After Henry Bence Jones Discovered Urinary Proteins With Unusual Thermal Properties Among Multiple Myeloma Patients It has been more than a century since the light polypeptide proteins (κ and λ chains) of immunoglobulin molecules have been known. It is known that the mixture of free κ and λ light chains containing very small polyclonal sources in normal urine