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经皮接种 (TCI)是一种新颖的免疫接种策略 ,它通过在皮肤表面外敷抗原和佐剂 ,导致血清和粘膜分泌液中抗原 /佐剂特异性Ig G的产生。作者以具有不同 H- 2主要组织相容性复合体 (MHC)基因的 C5 7BL/ 6、BALB/ c和 C3H品系小鼠为对象 ,以霍乱毒素 (CT)为抗原或作为白喉类毒素 (DT
Transdermal inoculation (TCI) is a novel immunization strategy that results in the production of antigen / adjuvant-specific IgG in serum and mucosal secretions by external application of antigens and adjuvants on the surface of the skin. The aim of this study was to investigate the effects of cholera toxin (CT) as antigens or as a marker of diphtheria toxoid (DT) in mice with C5 7BL / 6, BALB / c and C3H lines with different major Hm2 histocompatibility complex