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目的探讨垂体后叶素和心得安联合应用治疗肝硬化门脉高压出血的临床效果。方法回顾性分析我院收治的94例肝硬化门脉高压出血患者,随机分为2组,治疗组50例,采用垂体后叶素和心得安联合治疗;对照组44例,采用垂体后叶素治疗,比较两组效果。结果临床疗效比较治疗组总有效率96%,对照组总有效率70.5%,治疗组总有效率明显高于对照组,差异有统计学意义。不良反应比较,治疗组有2例出现胸闷,4例出现腹痛、大便次数增多等症状,对照组5例出现胸闷,3例出现心律失常,5例出现心前区疼痛,4例出现腹痛、大便次数增多等症状。结论垂体后叶素与心得安联合应用可有效降低门静脉压力,收缩内脏血管,消除不良反应,提高患者的治愈率,值得在临床中广泛应用。
Objective To investigate the clinical effect of combination of pituitrin and propranolol in the treatment of portal hypertension with cirrhosis. Methods A retrospective analysis of 94 cases of patients with portal hypertension in our hospital were randomly divided into two groups, the treatment group of 50 cases, the combination of pituitrin and propranolol; control group of 44 patients with pituitrin Treatment, the two groups were compared. Results The clinical curative effect was 96% in the treatment group and 70.5% in the control group. The total effective rate in the treatment group was significantly higher than that in the control group, the difference was statistically significant. In the control group, there were 2 cases of chest tightness, 4 cases of abdominal pain and increased stool frequency, 5 cases of chest tightness, 3 cases of arrhythmia, 5 cases of precordial pain and 4 cases of abdominal pain and stool Increase the number of other symptoms. Conclusions The combination of pituitrin and propranolol can effectively reduce the pressure of portal vein, reduce visceral blood vessels, eliminate adverse reactions and improve the cure rate of patients. It is worth widely used in clinical practice.