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一般资料:年龄:34～81岁,平均年龄43.3岁。男8例,女3例,发病前1～4周有上感史者9例,有腹泻史者1例,无诱因者1例。11例中除1例亚急性起病外,均为急性起病。 临床表现:头晕5例,走路不稳9例。四肢麻木无力8例,单纯双下肢无力1例。视物不清5例,复视7例。饮水呛咳3例,声音嘶哑、语言含糊不清2例,吞咽困难3例。胸闷2例。查体:11例病人均有眼球活动障碍,其中5例固定,5例双侧外展差,1例单侧外展差。瞳孔散大双侧4例,单侧2例。光反射消失5例。11例病人均有不同程度眼睑下垂(其中完全下垂者2例)。周围性面瘫6例,表现单侧中枢性面瘫1例。软腭活动差双侧3例,单侧1例。角膜反射迟钝1列。四肢肌力Ⅴ级6例,肌力Ⅳ级级5例。11例病人肌张力均低。腱反射除1例减弱外,其余均消失。指鼻试验,跟膝胫试验双侧均差。末梢型感觉障碍3例。
General Information: Age: 34 ~ 81 years old, average age 43.3 years old. There were 8 males and 3 females, 9 cases had a history of sensation 1 to 4 weeks before onset, 1 case had history of diarrhea, and 1 case had no predisposition. In 11 cases, except for 1 subacute onset, all were acute onset. Clinical manifestations: 5 cases of dizziness, walking instability in 9 cases. Numbness numbness in 8 cases, simple lower extremity weakness in 1 case. 5 cases of blurred vision, diplopia in 7 cases. Choking cough in 3 cases, hoarseness, vague language 2 cases, 3 cases of dysphagia. 2 cases of chest tightness. Examination: 11 patients had eye movement disorders, including 5 cases of fixed, 5 cases of poor bilateral abduction, 1 case of unilateral abduction. Mydriasis were bilateral in 4 cases, unilateral in 2 cases. Light reflection disappeared in 5 cases. Eleven patients had different degrees of ptosis (including 2 cases of complete prolapse). Peripheral facial paralysis in 6 cases, the performance of unilateral central facial paralysis in 1 case. Soft palate activity was poor bilateral in 3 cases, unilateral in 1 case. Corneal reflex slow 1 column. Grade Ⅴ limbs in 6 cases, Ⅳ grade muscle strength in 5 cases. Eleven patients had low muscle tone. Tendon reflex except one case weakened, the rest are disappeared. Finger nose test, both knee and shin test were poor. Peripheral sensory disturbance in 3 cases.