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采用脉冲辐解技术,在pH=7的磷酸缓冲溶液中,以AQS为参比物,用动力学的方法测定了12个自行设计合成的新型放射增敏化合物的单电子还原电位值E,作为初步评价亲电子性化合物的增敏作用的指标之一。它们的单电子还原电位值E在-420~-490mV之间,表明这类化合物具有一定的亲电子性。
Using pulse radiolysis technology, 12 single-electron reduction potential values E of 12 novel self-designed radiosensitizing compounds were determined by the kinetic method in pH = 7 phosphate buffer solution with AQS as the reference material. Preliminary evaluation of electrophilic compounds one of the indicators of sensitization. Their single electron reduction potential E between -420 ~ -490mV, indicating that these compounds have a certain electrophilic.