目的 :观察缺氧复氧时家兔主、肺和肾的动脉血管反应性的变化。方法 :用生物测定法观察缺氧复氧时家兔主、肺和肾动脉的舒缩反应 ,用张力传感器记录血管环张力变化。结果 :缺氧后 ,有内皮的各动脉环均产生短暂的缺氧性收缩 ,以肾动脉单位重量的收缩力最大 ;具有一定张力的各动脉环复氧后立即舒张 ,随后明显收缩。有内皮的各动脉环复氧后的舒张反应无明显差异。而收缩反应仍以肾动脉最明显 ,肺动脉其次。去除内皮后 ,各动脉环缺氧性收缩消失。主、肾动脉复氧后的舒张减弱 ,而肺动脉复氧后的舒张无变化。主、肾动脉收缩反应显著增强 ,肺动脉复氧性收缩反而降低。结论 :主、肺和肾动脉缺氧复氧后血管舒缩改变不同与内皮功能的差异有关 Objective: To observe the changes of arterial vasoreactivity in the main, lung and kidney of rabbits during hypoxia / reoxygenation. Methods: The biomechanical assay was used to observe the systolic and diastolic responses of the main artery, lung and renal arteries in hypoxia and reoxygenation rats. Tension sensors were used to record the changes of vascular tension. Results: After hypoxia, there was a transient hypoxic contraction in every arterial ring with endothelium and the largest contractile force in the unit of renal artery. The diastolic pressure of each arterial ring with some tension was relieved immediately after reoxygenation and then significantly contracted. Endothelium of the arterial rings after reoxygenation no significant difference in relaxation response. The contractile response is still the most obvious renal artery, followed by pulmonary artery. After removal of the endothelium, the arterial annulus hypoxia contraction disappeared. The main, renal arteries after reoxygenation weakened, while pulmonary artery reoxygenation did not change after diastole. The main renal artery systolic response was significantly enhanced pulmonary reoxygenation contractions but decreased. Conclusion: The changes of vasomotor after hypoxia-reoxygenation in primary, pulmonary and renal arteries are related to the difference of endothelial function