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孟鲁司特钠咀嚼片属于白三烯类受体拮抗剂,白三烯作为哮喘气道炎性反应中的重要炎性介质,在哮喘的发病中发挥重要作用:促进炎性细胞在气道的聚集;引起气道平滑肌收缩、黏液分泌增加及血管通透性增加;促进气道重塑,引起气道高反应。近来年随着抗白三烯类药物在哮喘治疗中的作用越来越引起人们的关注,临床的广泛应用,不良反应的病例报道也有所增多,国外及国内多项研究显示孟鲁司特钠可诱发儿童精神
The montelukast sodium chewable tablets belong to the leukotriene receptor antagonist. Leukotrienes play an important role in the pathogenesis of asthma as an important inflammatory mediator in the airway inflammatory reaction of asthma: promoting inflammatory cells in the airways ; Cause airway smooth muscle contraction, increased mucus secretion and increased vascular permeability; promote airway remodeling, causing airway hyperresponsiveness. In recent years, with the anti-leukotriene treatment of asthma in the role of more and more cause for concern, the clinical application of a wide range of cases of adverse reactions have also increased, a number of foreign and domestic studies have shown that montelukast sodium Children can be induced spirit