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对60岁以上老年肺癌及良性肺疾病患者各20例进行支气管肺泡灌洗,并测定灌洗液中CEA、SIgA含量,同时测血清CEA。肺癌组灌洗液中CEA、SIgA分别为39.47±31.12μg/L及291.5±149.17mg/L,均明显高于良性肺疾病组11.2±4.87μg/L及93.65±63.5mg/L(P<0.01)。按CEA>15μg/L、SIgA>120mg/L为阳性诊断值,肺癌组阳性率分别为75％及55％,良性组为15％及10％。对20例肺癌患者观察纤支镜插入前后及灌洗时血氧饱和度变化,部分患者有轻度下降,但5～10min即可恢复至原有水平。
The bronchoalveolar lavage was performed on 20 patients with lung cancer and benign lung diseases in the elderly over 60 years old. The levels of CEA and SIgA in the lavage fluid were measured, and serum CEA was measured at the same time. The levels of CEA and SIgA in lavage fluid of lung cancer group were 39.47±31.12μg/L and 291.5±149.17mg/L, respectively, which were significantly higher than 11.2±4.87μg/L and 93.65±63.5mg/L in benign lung disease group (P<0.01). ). According to CEA>15μg/L and SIgA>120mg/L, the positive rate was 75% in lung cancer group and 55% in lung cancer group, and 15% and 10% in benign group. In 20 patients with lung cancer, changes in blood oxygen saturation before and after bronchofiberoscope insertion and lavage were observed, and some patients had a slight decrease, but they recovered to their original levels within 5 to 10 minutes.