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目的:探讨血微量元素对小儿反复呼吸道感染的影响。方法:对1100例临床诊断反复呼吸道感染患儿,用北京博辉公司的BH2100原子吸收光谱仪及配套试剂检测血铅和BH5100型多通道原子吸收光谱仪测量人体镉(Cd)、铜(Cu)、锌(Zn)、钙(Ca)、镁(Mg)、铁(Fe)6种元素含量,并与600例门诊体检的健康儿童血微量元素进行对照。结果:反复呼吸道感染患儿0～2岁组血Pb高,血Cu、Zn、Ca、Fe低;3～5岁组血Cu、Zn、Ca、Mg、Fe均低;6～12岁组血Zn、Ca、Mg、Fe低,与对照组比较有显著差异;0～2岁患儿血Pb与Fe、Cd呈明显负相关,与Cu、Zn、Ca、Mg呈正相关;3～5岁患儿铁与钙、锌含量均呈显著正相关;6～12岁患儿Zn与Ca呈显著正相关;0～2岁频发下呼吸道感染患儿Fe和Zn明显低;3～5岁频发下呼吸道感染患儿以Zn缺乏为主。结论:微量元素对小儿反复呼吸道感染的发生和病情有一定影响。
Objective: To investigate the effect of blood trace elements on recurrent respiratory tract infections in children. Methods: One hundred and thirteen children with recurrent respiratory tract infection were enrolled in this study. The levels of cadmium (Cd), copper (Cu), zinc (Ⅱ) and zinc (Ⅲ) in blood were measured with BH2100 atomic absorption spectrometer (Zn), calcium (Ca), magnesium (Mg) and iron (Fe) were measured and compared with the blood trace elements of healthy children in 600 outpatients. Results: The levels of Pb, Cu, Zn, Ca and Fe were low in children aged 0-2 years with recurrent respiratory tract infection. The levels of Cu, Zn, Ca, Mg and Fe were lower in patients aged 3 to 5 years. Zn, Ca, Mg and Fe were significantly lower than those in control group. There was a negative correlation between Pb and Fe and Cd in children aged 0 ~ 2 years and a positive correlation with Cu, Zn, Ca and Mg, Children’s iron and calcium, zinc content were significantly positive correlation; children aged 6 to 12 Zn and Ca was significantly positive; 0 to 2-year-old children with lower respiratory tract infection Fe and Zn was significantly lower; 3 to 5 years of age Lower respiratory tract infection in children with Zn-based. Conclusion: Trace elements have a certain influence on the occurrence and condition of recurrent respiratory tract infections in children.