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近年研究发现三磷酸腺苷敏感性钾通道 (KATP)开放是心肌保护的关键。钾通道开放剂 (PCOs)可选择性作用于心肌的KATP,通过抑制钙内流降低细胞兴奋性及耗氧量。PCOs对心肌保护的作用及机制等方面作一综述。
Recent studies have found that ATP-sensitive potassium channel (KATP) opening is the key to myocardial protection. Potassium channel openers (PCOs) selectively act on KATP in the myocardium and reduce cell excitability and oxygen consumption by inhibiting calcium influx. PCOs on the role of myocardial protection and mechanisms such as a review.