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目的观察雷贝拉唑钠肠溶胶囊联合元胡胃舒胶囊治疗胃食管反流病临床疗效。方法胃食管反流病患者110例,随机分为对照组和观察组,各55例,对照组患者应用雷贝拉挫钠肠溶胶囊治疗,观察组则予以雷贝拉挫钠肠溶胶囊联合元胡胃舒胶囊治疗,分析比较两组治疗效果及不良反应。结果观察组临床症状改善情况明显优于对照组(P<0.05),观察组总有效率92.3%,显著高于对照组65.6%,差异有统计学意义(P<0.05),两组患者不良反应发生率差异无统计学意义(P>0.05)。结论雷贝拉唑钠肠溶胶囊与元胡胃舒胶囊联用治疗胃食管反流病效果显著,安全性高,值得临床推广。
Objective To observe the clinical efficacy of rabeprazole sodium enteric-coated capsules combined with Yuanhu Weishu capsule in the treatment of gastroesophageal reflux disease. Methods A total of 110 patients with gastroesophageal reflux disease were randomly divided into control group and observation group, 55 cases in each group. Patients in the control group were treated with enteric-coated capsules of rabeprazole sodium, Yuan Hu Weishu capsule treatment, analysis and comparison of the two groups of treatment and adverse reactions. Results The improvement of clinical symptoms in the observation group was significantly better than that in the control group (P <0.05). The total effective rate in the observation group was 92.3%, significantly higher than that in the control group (65.6%), with significant difference (P <0.05) The difference was not statistically significant (P> 0.05). Conclusion Rabeprazole sodium enteric-coated capsules and Yuanhu Weishu capsule combined with the treatment of gastroesophageal reflux disease has a significant effect, high safety, worthy of clinical promotion.