肺癌患者气道高反应性的分析

来源 :华西医学 | 被引量 : 0次 | 上传用户:shadao
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
目的研究肺癌患者的气道高反应性和肺通气功能情况,并探讨其易感因素,为肺癌患者肺通气功能的临床评估提供依据。方法对2010年4月2011年4月收治的40例肺癌患者(A组)进行术前肺功能检测及气管激发试验,选取同期的健康体检者40例做对照组(B组),并采用logistic逐步回归分析肺癌患者的气道高反应性的易感因素。结果①A组患者的用力肺活量、第1秒用力呼气容积(forced expiratory volume in one second,FEV1)、最高呼气流量(peak expiratory flow,PEF)以及最大呼气中期流量均小于B组,且差异有统计学意义(P=0.000);②A组的FEV1估计异常人数和PEF估计异常人数均多于B组(P<0.05);③A组组胺气道激发试验阳性者多于B组(χ2=5.000,P=0.025),且A组PD20FEV1低于对照组[分别为(4.69±0.82)、(8.32±1.43)μmol/L;t=13.930,P=0.000];④logistic逐步回归分析表明影响A组患者的气道高反应性的因素为年龄、分型、TNM分期、病史、吸烟。结论肺癌气道反应性增高,且肺功能下降,由于肺癌气道高反应性的易感因素较多,因此需对合并因素较多者进行及时的预防,防止由于气道阻力增加和气道狭窄引起的胸闷、咳嗽、喘息和呼吸困难等症状。 Objective To study the airway hyperresponsiveness and pulmonary ventilation in patients with lung cancer and to explore the predisposing factors for lung function in patients with lung cancer. Methods Forty lung cancer patients (group A) treated in April 2010 and April 2011 were enrolled in this study. Preoperative pulmonary function test and tracheal provocation test were performed. Forty healthy subjects in the same period were selected as control group (group B) Stepwise regression analysis of susceptibility to airway hyperresponsiveness in lung cancer patients. Results ① The forced vital capacity, forced expiratory volume in one second (FEV1), peak expiratory flow (PEF) and maximum expiratory flow in group A were lower than those in group B, and the differences (P = 0.000); ②The abnormality of FEV1 and abnormal PEF in group A were more than that of group B (P <0.05); ③A group had more positive histamine-induced airway stimulation than group B (χ2 = 5.000, P = 0.025). The PD20FEV1 in group A was lower than that in control group [(4.69 ± 0.82) and (8.32 ± 1.43) μmol / L, respectively; t = 13.930, P = Patients with airway hyperresponsiveness factors for age, type, TNM stage, history, smoking. Conclusions The airway responsiveness of lung cancer is increased and the lung function is decreased. Because of the more susceptible factors of airway hyperresponsiveness in lung cancer, it is necessary to timely prevent the more complicated factors and prevent it from being caused by the increase of airway resistance and airway stenosis Chest tightness, cough, wheezing and breathing difficulties and other symptoms.
其他文献
十年光阴,十年精彩,我们见证了J.K.Rowling笔下这些小魔法师的每一步成长,从他们第一次踏上霍格沃茨特快,到最终战胜Voldemort(伏地魔)拯救世界。然而,盛宴终有散去时,我们唯
由烟台市文学艺术界联合会、烟台市赏石研究会、烟台市观赏石汇展中心主办的“中国·烟台第五届观赏石 Yantai Literary and Art Circles Federation, Yantai City Apprecia
噢,是什么从海上来,rn过了沙洲过了浅滩;rn是什么回到我身边来rn航得快,航得慢?
请下载后查看,本文暂不支持在线获取查看简介。 Please download to view, this article does not support online access to view profile.
期刊
本文主要针对高职学生怕数学、不愿学数学的现象,提出转变教学观念,从认识数学、改进课堂教学、培养学习数学兴趣等方面谈谈如何帮助学生学习好数学.
请下载后查看,本文暂不支持在线获取查看简介。 Please download to view, this article does not support online access to view profile.
新闻事件:《色戒》改编自张爱玲小说。依靠市场运作,以女演员和男演员两场全裸体的 ML 场面为点,展开声势浩大的爆炒,从网络到平面电视电台,影响巨大。从销售衡量这部电影成
利用磁控溅射法在医用钛合金Ti6Al4V表面制备Ti-Ag、Ti-Ag-N薄膜。采用扫描电子显微镜、X射线衍射、X射线能量色散谱、X射线光电子能谱分析薄膜的表面形貌、微观结构、化学成
Dear建阳:你好!小编在下班时间拥挤的地铁里读着你的信,刚读到第一段,便禁不住会心一笑,引得旁人侧目——你说你非常喜欢Teens,不仅仅是因为它对学习有帮助,还因为它总是带给你快乐
日本盆花协会理事长加藤孝义从中国进口花卉已有10多年的历史,与中国很多花卉企业做过生意。如今他每年多次前往中国考察,对中国花卉企业及整个产业有自己的认识。在第五届中