小花棘豆是豆科棘豆属多年生草本植物。可供药用,具麻醉、镇痛之功效,用于关节炎、牙痛、神经衰弱等疾病的治疗。该植物主要分布在我国的内蒙古及西北大部分地区。该植物适宜在干旱沙漠地区生长,每逢干旱年份,其它牧草稀疏,而此植物生长茂盛,牲畜因饥饿被迫采食到一定量后,即可引起中毒乃至死亡,给畜牧业生产造成严重损失。关于小花棘豆的有毒成分,国内外尚无明确报道。有人曾认为该植物引起家畜中毒乃其含硒量过高所致。但据内蒙古农牧学院等对采食小花棘豆中毒的病羊的肝、毛含硒量进行测定的结果,发现其含硒量均不超出正常范围。为了探索小花棘豆中毒的机理,我们对小花棘 Oxytropis fragrans is a perennial herb belonging to the family Otricle. It can be used medicinally, has the effects of anesthesia and analgesia, and is used for the treatment of diseases such as arthritis, toothache and neurasthenia. The plant is mainly distributed in Inner Mongolia and most of the northwest region of China. The plant is suitable for growing in arid desert areas. In dry years, other pastures are sparse, and the plant is flourishing. After the animal is forced to feed a certain amount due to hunger, it can cause poisoning and even death, causing serious losses to the animal husbandry production. . With regard to the toxic components of Oxytropis sinensis, there are no clear reports at home and abroad. Some people once thought that the plant caused livestock poisoning due to its high selenium content. However, according to the determination of the selenium content of the liver and wool of the diseased sheep that had been poisoned by Oxytropis sinensis in Inner Mongolia Academy of Agriculture and Animal Husbandry, it was found that the selenium content did not exceed the normal range. In order to explore the mechanism of Oxytoxin poisoning, we