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目的探讨雾化吸入3%NaCl溶液(简称高渗盐水)和氨哮素治疗毛细支气管炎的临床疗效。方法采取随机对照方法,将208例毛细支气管炎患儿分成治疗组和对照组,治疗组106例,雾化吸入高渗盐水3ml+8μg氨哮素,3次/d;对照组102例,雾化吸入生理盐水3ml+地塞米松和α-糜蛋白酶5mg加入生理盐水中,3次/d;疗程为雾化至患儿痊愈,观察两组临床症状、体征改善情况并对比其疗效。结果疗效比较,治疗组总有效率99.1%,对照组总有效率89.2%;治疗组与对组主要症状与体征比较,喘照息缓解时间平均缩短1.5d;咳嗽缓解时间平均缩短1.1d;住院时间平均缩短1.9d。经统计学处理,差异均有统计学意义(P<0.05)结论雾化吸入高渗盐水和氨哮素治疗毛细支气管炎,能有效改善毛细支气管炎喘息症状,缩短住院时间,疗效更显著。
Objective To investigate the clinical efficacy of nebulized inhalation of 3% NaCl solution (hypertonic saline) and amikacin for the treatment of bronchiolitis. Methods Totally 208 children with bronchiolitis were divided into treatment group and control group. 106 cases in treatment group were treated with nebulized hypertonic saline (3ml + 8μg aminopterin, 3 times / d), 102 cases in control group Inhaled saline 3ml + dexamethasone and α-chymotrypsin 5mg added to normal saline, 3 times / d; course of treatment for the recovery of children with nebulization, the clinical symptoms and signs were observed to improve the situation and compared its efficacy. Results The total effective rate was 99.1% in the treatment group and 89.2% in the control group. The main symptoms and signs in the treatment group and the control group were shortened 1.5d on average; the average time for relieving cough was 1.1d; The average time to shorten 1.9d. After statistical analysis, the difference was statistically significant (P <0.05) Conclusion The inhalation of hypertonic saline inhalation of ammonia and the treatment of bronchiolitis, ammonia, can effectively improve the symptoms of bronchiolitis and shorten the length of stay, the effect is more significant.